Chemotaxin-induced changes in cyclic adenosine monophosphate levels in human neutrophils
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منابع مشابه
Dissociations between changes in myocardial cyclic adenosine monophosphate and contractility.
The relationship between changes in the myocardial concentration of adenosine 3':5'-cyclic monophosphate (cyclic AMP) and cardiac contractility was studied in guinea pig and rat myocardium. When isolated perfused guinea pig heart were perfused with 10-5-M papaverine, a potent inhibitor of cyclic AMP phosphodiesterase activity, myocardial cyclic AMP concentration increased significantly from 1.7...
متن کاملDissociations between Changes in Myocardial Cyclic Adenosine Monophosphate
The relationship between changes in the myocardial concentration of adenosine 3':5'-cyclic monophosphate (cyclic AMP) and cardiac contractility was studied in guinea pig and rat myocardium. When isolated perfused guinea pig hearts were perfused with 10"M papaverine, a potent inhibitor of cyclic AMP phosphodiesterase activity, myocardial cyclic AMP concentration increased significantly from 1.7 ...
متن کاملNephrogenous Cyclic Adenosine Monophosphate
An abstract ofthis work appeared in 1976. Clin. Res. 24: 456A. (Abstr.) Dr. Broadus' present address is Division of Endocrinology, Department of Internal Medicine, Yale University, New Haven, Conn. 06510. Received for publication 20 April 1976 and in revisedform 13 June 1977. the validity of the measurements and the expressions employed.
متن کاملRetinoblastoma protein is rapidly dephosphorylated by elevated cyclic adenosine monophosphate levels in human B-lymphoid cells.
Elevated cyclic AMP levels induce a rapid block in the mid-G1 phase of the cell cycle in B-lymphoid Reh cells, accompanied by a transient block in G2. The retinoblastoma (Rb) gene product has been implicated as a key regulator of eukaryotic cell growth. The Rb protein enforces its growth-suppressive effect in early G1, where it is underphosphorylated and firmly bound in the nucleus. A possible ...
متن کاملIncreased levels of cyclic adenosine-3',5'-monophosphate in human polymorphonuclear leukocytes after surface stimulation.
Levels of cyclic AMP (cAMP) (but not cyclic GMP) in suspensions of human polymorphonuclear leukocytes (PMN) increased promptly after exposure of the cells to stimuli such as the chemotactic peptide N-formyl methionyl leucyl phenylalanine, the immune complex bovine serum albumin/anti-bovine serum albumin and calcium ionophore A23187. cAMP increased rapidly, reaching a maximum of twice the basal ...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1980
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.29.1.284-286.1980